Access LegoGen at Nanohub here. You will need a Nanohub account in order to use LegoGen.
Legogen is a tool for converting arbitrary CAD models into DNA nanostructures through the DNA brick method. It provides files suitable for all-atom molecular dynamics simulations in NAMD, as well as a list of nucleotide sequences for use in experiments. Legogen allows you to design complex structures with ease, especially when the overall shape of the structure is the design focus. The internal connectivity is automated by LegoGen, as well as the nucleotide sequences, allowing designs to be created in a fraction of the usual time. By taking advantage of DNA brick structures having no central scaffold strand traversing through the entire structure, vastly different structures can be built from a dedicated strand library, rather than custom strands for each structure. This also allows structures to be designed iteratively, with modifications to existing designs requiring fewer new strands than brand new designs.