Kumar Sarthak
e-mail: 
kumars2@illinois.edu
phone: 
(217) 904-2141
office: 
265 LLP

Loomis Laboratory of Physics
1110 West Green Street
Urbana, IL 61801-3080

I received my Bachelors of Science degree in Chemistry and Physics from Indian Institute of Science in 2017. I am currently working on using biological nanopores for protein sequencing.

Publications

  1. Hadjer Ouldali, Kumar Sarthak, Tobias Ensslen, Fabien Piguet, Philippe Manivet, Juan Pelta, Jan C. Behrends, Aleksei Aksimentiev, and Abdelghani Oukhaled. "Electrical recognition of the twenty proteinogenic amino acids using an aerolysin nanopore." Nature Biotechnology 38:176-181 (2020). PDF icon Supplementary Information (15.98 MB)
  2. James Wilson, Kumar Sarthak, Wei Si, Luyu Gao, and Aleksei Aksimentiev. "Rapid and Accurate Determination of Nanopore Ionic Current Using a Steric Exclusion Model." ACS sensors 4:634-644 (2019). PDF icon sem_si.pdf (4.02 MB)
  3. Tobias Ennslen, Kumar Sarthak, Aleksei Aksimentiev, and Jan C. Behrends. "Resolving Isomeric Posttranslational Modifications Using a Biological Nanopore as a Sensor of Molecular Shape." Journal of the American Chemical Society (2022). PDF icon supplementary_information.pdf (4.85 MB)
  4. Florian Leonardus Lucas, Kumar Sarthak, Erica Mariska Lenting, David Coltan, Nieck Jordy van der Heide, Roderick Corstiaan Versloot, Aleksei Aksimentiev, and Giovanni Maglia. "The Manipulation of the Internal Hydrophobicity of FraC Nanopores Augments Peptide Capture and Recognition." ACS Nano (2021). PDF icon nn0c09958_si_001.pdf (1.59 MB)
  5. Javier Antonio Alfaro, Peggy Bohländer, Mingjie Dai, Mike Filius, Cecil J. Howard, Xander F. van Kooten, Shilo Ohayon, Adam Pomorski, Sonja Schmid, Aleksei Aksimentiev, Eric V. Anslyn, Georges Bedran, Chan Cao, Mauro Chinappi, Etienne Coyaud, Cees Dekker, Gunnar Dittmar, Nicholas Drachman, Rienk Eelkema, David Goodlett et al. "The emerging landscape of single-molecule protein sequencing technologies." Nature Methods 18 (2021).
  6. Adnan Choudhary, Himanshu Joshi, Han-Yi Chou, Kumar Sarthak, James Wilson, Christopher Maffeo, and Aleksei Aksimentiev. "High-Fidelity Capture, Threading, and Infinite-Depth Sequencing of Single DNA Molecules with a Double-Nanopore System." ACS Nano 14:15566-15576 (2020). PDF icon nn0c06191_si_001.pdf (547.55 KB)