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    Self-folding water filter
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    Infinite-depth sequencing of single nucleic acid molecules
  • #003366
    Mrdna: Multi-resolution DNA modeling package blends speed and accuracy for structure determination
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    Nanopore recognition of the twenty amino acids
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    Predicting energy production of entire photosynthetic organelle from atomic simulations
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    Artificial water channels enable rapid and selective water transport
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    Guiding the capture of DNA molecules and proteins
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    Outperforming nature: synthetic enzyme built from DNA flips lipids of biological membranes at record rates
  • #ff9900
    Under Pressure: repellant nanopores
  • #000099
    Simulations capture diffusive substeps of a protein moving along ssDNA

Recent publications

Membrane Activity of a DNA-Based Ion Channel Depends on the Stability of Its Double-Stranded Structure

Diana Morzy, Himanshu Joshi, Sarah E. Sandler, Aleksei Aksimentiev, and Ulrich F. Keyser
Nano Letters 21(22) 9789-9796 (2021)
DOI:10.1021/acs.nanolett.1c03791  BibTex

DNA Origami Voltage Sensors for Transmembrane Potentials with Single-Molecule Sensitivity

Sarah E. Ochmann, Himanshu Joshi, Ece Büber, Henri G. Franquelim, Pierre Stegemann, Barbara Saccà, Ulrich F. Keyser, Aleksei Aksimentiev, and Philip Tinnefeld
Nano Letters 21(20) 8634-8641 (2021)
DOI:10.1021/acs.nanolett.1c02584  BibTex

Synthetic Macrocycle Nanopore for Potassium-Selective Transmembrane Transport

Dan Qiao, Himanshu Joshi, Huangtianzhi Zhu, Fushi Wang, Yang Xu, Jia Gao, Feihe Huang, Aleksei Aksimentiev, and Jiandong Feng
Journal of the American Chemical Society 143(39) 15975-15983 (2021)
DOI:10.1021/jacs.1c04910  BibTex

A tetrahedral DNA nanorobot with conformational change in response to molecular trigger

Fengyu Liu, Xiaoming Liu, Qing Shi, Christopher Maffeo, Masaru Kojima, Lixin Dong, Aleksei Aksimentiev, Qiang Huang, Toshio Fukuda, and Tatsuo Arai
Nanoscale (2021)
DOI:10.1039/D1NR02757C  BibTex

The emerging landscape of single-molecule protein sequencing technologies

Javier Antonio Alfaro, Peggy Bohländer, Mingjie Dai, Mike Filius, Cecil J. Howard, Xander F. van Kooten, Shilo Ohayon, Adam Pomorski, Sonja Schmid, Aleksei Aksimentiev, Eric V. Anslyn, Georges Bedran, Chan Cao, Mauro Chinappi, Etienne Coyaud, Cees Dekker, Gunnar Dittmar, Nicholas Drachman, Rienk Eelkema, David Goodlett et al.
Nature Methods 18 (2021)
DOI:10.1038/s41592-021-01143-1  BibTex